PENGARUH PEMBERIAN SARI BUAH JAMBU BIJI (Psidium guajava Linn.) TERHADAP KADAR TRIGLISERIDA MENCIT BALB/c

Abstrak

Abstract : Diabetes mellitus is caused by insulin resistance is disrupted so that the
hormone sensitive lipase in adipose tissue will become active and lipolysis is
increased, Psidium guajava is known to have a hypertriglyceride effect that can be
useful. This study aims to determine the effect of Psidium guajava juice on
triglyceride levels of BALB / c mice in induction of sucrose load. The research type is
true-experiment with pretest-posttest with control group design. This research was
conducted with 20 BALB / c mice which were given 10% sucrose for 15 days. The
intervention was Psidium guajava with three dose variations: 0.25 ml / 20gBB, 0,50
ml / 20gBB and 1.00 ml / gBB for 7 days. Data analysis using one-way ANOVA test
followed by post-hoc LSD test. The results showed that there were significant
differences between treatment group X1 and treatment group X3. A significant
decrease in triglyceride levels was found in the dose group of 1.00 ml/20 gBB with
the dose group 0,25 ml/20gBB. It is recommended in subsequent research to identify
the active compounds contained in Psidium guajava in providing health.
Keywords: Diabetes mellitus, Triglycerides, Psidium guajava.